An Unusual Histopathological Presentation of Mandibular Osteosarcoma

Authors

*Saja A. Alramadhan, University of Mississippi Medical CenterFollow
Rutvi Vyas, University of Detroit Mercy School of Dentistry
Indraneel Bhattacharyya, University of Florida College of Dentistry
Mohammed N. Islam, University of Florida College of Dentistry
John D. Reith, Department of Pathology, Cleveland Clinic

Author Type

faculty

Document Type

Article

Source Publication Title

An Unusual Histopathological Presentation of Mandibular Osteosarcoma

Abstract

Jaw osteosarcoma (JOS) is a rare, distinct variant that differ from long bone osteosarcoma (LBOS) in several aspects. JOS typically appears about twenty years later than LBOS, displays a lower propensity for metastasis to other organs, and exhibits better survival rates. The dissimilarities in clinical and biological behavior between JOS and LBOS are likely due, at least in part, to variations in their respective microenvironments. In this report, we present a case of OS affecting the mandible in a young patient. This case displayed classic radiographic features but a unique histopathological presentation, posing a diagnostic challenge for pathologists, especially if encountered in small biopsies.

DOI

10.1007/s12178-024-09925-8

Publication Date

11-19-2024

Comments

The version of record of this article, first published in Head and Neck Pathology, is available online at Publisher’s website: https://doi.org/10.1007/s12105-024-01724-4

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Alramadhan, *Saja A.; Vyas, Rutvi; Bhattacharyya, Indraneel; Islam, Mohammed N.; and Reith, John D., "An Unusual Histopathological Presentation of Mandibular Osteosarcoma" (2024). Oral-Maxillofacial Surgery and Pathology. 1.
https://digitalcollections.umc.edu/oral-maxpub/1