Document Type
Article
Publication Title
Monocyte and Macrophage Functions in Oncogenic Viral Infections
Abstract
Monocytes and macrophages are part of innate immunity and constitute the first line of defense against pathogens. Bone marrow-derived monocytes circulate in the bloodstream for one to three days and then typically migrate into tissues, where they differentiate into macrophages. Circulatory monocytes represent 5% of the nucleated cells in normal adult blood. Following differentiation, macrophages are distributed into various tissues and organs to take residence and maintain body homeostasis. Emerging evidence has highlighted the critical role of monocytes/macrophages in oncogenic viral infections, mainly their crucial functions in viral persistence and disease progression. These findings open opportunities to target innate immunity in the context of oncogenic viruses and to explore their potential as immunotherapies.
DOI
https://doi.org/10.3390/v16101612
Publication Date
10-15-2024
Recommended Citation
Echevarria-Lima, Juliana and Moles, Ramona, "Monocyte and Macrophage Functions in Oncogenic Viral Infections" (2024). Cell and Molecular Biology. 3.
https://digitalcollections.umc.edu/cell-molecular-biology/3
